Job Description
Salary:
Research Assistant : £31,396 to £32,982 per annum
Research Associate : £33,966 to £43,155 per annum
Newcastle University is a great place to work, with excellent benefits . We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.
Closing Date: 21 August 2023
The Role
This successful appointee will investigate the biology of endothelial cells in processes related to plaque erosion. It will combine analysis of patient-derived endothelial cells obtained from the clinic, with mechanistic studies under physiological and pathological flow that model the different blood flow patterns found in human coronary arteries. You will combine RNA sequencing, bioinformatics, pathway analysis and molecular biology techniques to investigate novel pathological mechanisms involved in the initiation of heart attacks.
In addition, you may be required to assist with other projects within the lab, relating to cardiovascular pathology.
You will analyse data and produce drafts of publications as well as give presentations on the findings to international conferences.
You will have a high level of academic achievement, and proven scientific ability in cardiovascular research. An ability to work within a team is critical.
Essential skills:
- A high level of subject knowledge in cardiovascular biology
- Excellent tissue culture skills, preferably with some experience of culture of endothelial cells under flow
- Ability to communicate complex information clearly, both orally and through the written word
- The ability to work collaboratively with colleagues
- The ability to use personal initiative and creativity to solve research problems
Desirable skills:
- RNA sequencing and bioinformatic pipelines
- Experience of working with primary endothelial cells in culture, particularly under physiological or pathological flow environments
- Generation and safe use of gene overexpression and knockdown vectors/technologies and use of transcription factor reporters
- Strong analytical skills and use of statistics
- Publication record in the in the area of cardiovascular biology
The successful appointee will join the Cardiovascular Group at Newcastle University ( https://www.ncl.ac.uk/medical-sciences/research/research-themes/vascular/ ) within Dr Stephen White’s lab, who is a new appointee at Newcastle.
This is a full time post, fixed term for 2 years
Further information can be obtained by contacting Dr Stephen White (via steve.white3@ncl.ac.uk )
Key Accountabilities
- Contribution to the research programme of the Institute under the clear guidance of a member of an academic staff or Principal Investigator
- Co-ordinate own work with that of others, deal with problems which may affect the achievement of research objectives and contribute to the planning of the project(s)
- Present information on research progress and outcomes to a Principal Investigator or groups overseeing the research project
- Work to deadlines and with support, manage competing priorities
- Ensure that personal knowledge in relevant fields of study is kept up to date
- Use research resources (including, where required, laboratories, workshops and specialist equipment) as appropriate
- Maintain academic standards and freedom, and work in accordance with university policies (e.g. equal opportunities, health and safety policies)
- Possible supervision and demonstration duties within undergraduate laboratories and example classes or in teaching small seminar classes
- Undertake relevant training and development activities to develop capacity for taking on wider responsibilities
- Develop, with advice, an awareness of own professional development needs and a personal development strategy
The Person
Knowledge, Skills and Experience
- An excellent record of academic achievement (in line with level of seniority)
- A high level of subject knowledge in cardiovascular biology
- Excellent tissue culture skills, preferably with some experience of culture of endothelial cells under flow.
- Ability to communicate complex information clearly, both orally and through the written word
- The ability to work collaboratively with colleagues
- The ability to use personal initiative and creativity to solve research problems
Desirable
- RNA sequencing and bioinformatic pipelines
- Experience of working with primary endothelial cells in culture, particularly under physiological or pathological flow environments
- Generation and safe use of gene overexpression and knockdown vectors/technologies and use of transcription factor reporters
- Strong analytical skills and use of statistics
- Publication record in the in the area of cardiovascular biology
Attributes and Behaviour
- Collegiate
- Open minded
- Conscientious with meticulous attention to detail
Qualifications
- Good honours degree (or equivalent) in a biology-related subject
- Essential for appointment at Research Associate level - a PhD in cardiovascular biology
Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.
We are committed to being a fully inclusive university which actively recruits, supports and retains colleagues from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all of our employees and the communities they represent. We are proud to be an equal opportunities employer and encourage applications from individuals who can complement our existing teams, we believe that success is built on having teams whose backgrounds and experiences reflect the diversity of our university and student population.
At Newcastle University we hold a silver Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC.
In addition, we are a member of the Euraxess initiative supporting researchers in Europe.
Requisition ID: 25876
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